Endocrine Abstracts

Introduction: Neuroendocrine tumors of head and neck region are rare and heterogeneous. it can arise in all the different organs of this region, including the nasal cavity, paranasal sinuses, larynx, thyroid, can be divided into two broad groups: those with epithelial differentiation, and neurally derived tumours, including paragangliomas and olfactory neuroblastomas. Their morphological and clinical features mainly depend on the degree of differentiation and on the site of or...

Introduction: Paragangliomas are a diverse group of neuroendocrine tumors arising from chromaffin cells within paraganglionic tissues of the autonomic nervous system.The aim of this study is to review our experience in the management of these tumors.Methods: The medical records of 12 patients with 13 paraganliomas was performed in a a single academic hospital over a period of 32 years from 1990 to 2022.Result...

Introduction: Addison’s disease was first described in 1855 by Thomas Addison as a result of adrenal insufficiency. It is most common in females aged 30–50 years. Symptoms are often non specific.Weakness and weight loss are universal features of Addison’s disease. It can present to a dermatologist in different ways. We present a case of a young female who reported to dermatology outdoor with a typical melasma-like eruption over her face.Ca...

Introduction: Necrobiosis lipoidica (NL) is a rare, chronic granulomatous cutaneous disease that most often affects the lower extremities. The etiology of the condition is unknown but there appears to be some association with diabetes mellitus. Perforating necrobiosis lipoidica (PNL) is a very rare variant of NL characterized by trans-epidermal collagen elimination. We present a case of type II diabetes patient with disseminated perforating necrobiosis lipoidica (PNL).<p c...

Introduction: Scleredema is a rare connective-tissue disorder characterized by diffuse, non-pitting induration of the skin. Scleredema is divided into three types. Pathogenesis is largely unknown. We present a case of a 56-year-old woman with non insulin-dependent diabetes mellitus who presented with a progressive history of thickening of the skin on her back.Case report: A 56-year-old woman, suffered from type 2 diabetes diagnosed 15 years ago, presente...